Depends, toilets have to maintain a minimum clearance from a wall which will give a centered forward approach but not a parrallel centered approach, Sinks is silent but all controls and soap dispensers must be within the reach range. Amirror would be almost usless unless the user is directly in front. Some are specific where the clear space needs to be.
602.2 The clear floor space shall be centered on the drinking fountain.
611.2 The clear floor space shall be centered on the appliance.
804.6.6 Refrigerator/Freezer. The centerline of the clear floor space shall be offset 24 inches (610 mm) maximum from the centerline of the dedicated spa
806.2.3 Beds.
Where beds are provided, clear floor space complying with Section 305 shall be provided on at least one side of the bed. The clear floor space shall be positioned for parallel approach to the side of the bed.