Sum and then round up is how I have always done it for the entire floor. Basically when you are doing a room by room calculation it is a net calculation versus a gross calculation. If the entire floor is a "B" occupancy and you calculate the entire floor at 100 sq ft per person you will probably not exceed the sum of all occupiable spaces when adding up all the fractional amounts' and then rounding up to the next whole number.
[BE] FLOOR AREA, GROSS. The floor area within the inside perimeter of the exterior walls of the building under consideration, exclusive of vent shafts and courts, without deduction for corridors, stairways, ramps, closets, the thickness of interior walls, columns or other features. The floor area of a building, or portion thereof, not provided with surrounding exterior walls shall be the usable area under the horizontal projection of the roof or floor above. The gross floor area shall not include shafts with no openings or interior courts.
[BE] FLOOR AREA, NET. The actual occupied area not including unoccupied accessory areas such as corridors, stairways, ramps, toilet rooms, mechanical rooms and closets.