You don't need insulation under the lower slab if you use an equivalent envelope approach to energy conservation. In other words, add enough insulation elsewhere in the envelope to allow the building to achieve a passing score on a COMCheck evaluation.
If you prefer to insulate under the slab, there are choices other than polyiso.
ROCKWOOL Comfortboard® 80 is a rigid exterior insulation board, providing a continuous layer of insulation around commercial or residential building envelopes.
www.rockwool.com
Thermafiber® RainBarrier® Dark™ continuous insulation with a bonded black facing designed for exceptional performance in rainscreen & cavity wall applications.
www.owenscorning.com
I wouldn't.
https://sbcindustry.com/fireprotectionfloorsqa